*Side Effects of Cytomel – Hypothyroidism: There has long since been a fear of thyroid medications among many people due to the issue of hypothyroidism, which simply refers to the thyroids inability to manufacture adequate amounts of thyroid hormones. The idea is simple, synthetic thyroid mediations are used, they are discontinued and at this stage the body no longer has the ability to make its own as it has become dependent on the exogenous hormones. Many fear they will become fat and uncontrollably so due to the T3 hormone playing such an important role on the metabolism. When it comes to the side effects of Cytomel, without question this one has been blown beyond out of proportion. It would truly take massive high dose long term use to truly cause hypothyroidism in an otherwise healthy adult. The thyroid will start making its own T3 very rapidly after use is discontinued, and at a much stronger rate than say testosterone after natural testosterone has been suppressed. That aside, in order to facilitate a smooth recovery it’s not a bad idea to drop down to a low dose for a week or two before discontinuing use completely. There’s no need to ramp down, simply drop down to a low maintenance dose and then discontinue.
Progesterone is produced from cholesterol with pregnenolone as a metabolic intermediate . In the first step in the steroidogenic pathway , cholesterol is converted into pregnenolone, which serves as the precursor to the progestogens progesterone and 17α-hydroxyprogesterone. These progestogens, along with another steroid, 17α-hydroxypregnenolone , are the precursors of all other endogenous steroids, including the androgens, estrogens, glucocorticoids, mineralocorticoids, and neurosteroids. Thus, many tissues producing steroids, including the adrenal glands , testes , and ovaries , produce progestogens.
Regardless of the phase of use or Equipoise doses in question, most men will need an anti- estrogen to combat this steroids aromatase activity. EQ does not aromatize heavily, but it does present enough estrogenic activity to promote related effects. Human Growth Hormone ( HGH ) is also a fantastic addition to any plan during any phase of use, and it is one of the most well-tolerated hormones you’ll ever come across. However, it is extremely expensive, requires long-term use (extremely long-term ) and we cannot call it essential.